RightAnswer Knowledge Solutions Search Results for Zafirlukast

New Search  |  Search Results (Zafirlukast)  |  Index of Example Chemical Results Pages
register now
RightAnswer Knowledge Solutions provides access to hundreds of data sources. Our premier and proprietary sources include fully-researched documents from well-established experts in the chemical and HazMat fields.

A search in our system for this chemical would return results – all in one place -- in the following categories from the listed data sources.
  • Chemical Identification
  • Environmental Hazards
  • First Aid/Medical Treatment
  • Handling/Storage/Shipping/Waste Management
  • Physical/Chemical Properties
  • Regulatory/Standards/Labels
  • Report Abstracts and Studies
  • Reproductive Risk
  • Toxicology/Health Hazards/Exposure
Example of Acute Exposure data from MEDITEXT.

RightAnswer Proprietary Data Sources:

MEDITEXT® Documentshelp

All Other Data Sources:

DART Documentshelp
HSDB® Data Bankhelp
LOLI® Listingshelp
REPROTOX® Documentshelp
RTECS® Registryhelp
Shepard's Cataloghelp
TERIS Documentshelp

ChemID External Links:

Other Government Links Searched via RegsKnowledge:

State Environmental Regulationshelp
CFR Regulationshelp

Example Content from MEDITEXT for Zafirlukast:

Please note: this is an extract of information from a larger document. Full document and details are available by subscription.


  1. USES: Zafirlukast is used for the prophylaxis and chronic treatment of asthma in adults and children 5 years of age and older.
  1. PHARMACOLOGY: Zafirlukast is a selective and competitive receptor antagonist of the cysteinyl leukotrienes D4 and E4. The cysteinyl leukotrienes, originally described as slow-reacting substances of anaphylaxis, produce airway edema, smooth muscle constriction, and altered cellular activity associated with the inflammatory process, all of which are associated with the pathophysiology of asthma.
  1. EPIDEMIOLOGY: Exposure is common, but severe toxicity is rare.
    1. ADVERSE EFFECT: Adverse effects associated with therapeutic zafirlukast use include headache, somnolence, pharyngitis, rhinitis, gastritis, elevation of liver enzymes, and asthma exacerbation; however, the incidence of most of these effects has been similar in placebo-treated patients.
    1. Zafirlukast and the other leukotriene antagonists have been associated with the development of Churg-Strauss Syndrome, a potentially fatal eosinophilic vasculitis, in adult asthma patients in most of whom concomitant oral steroid dose was reduced. Effects have included worsening pulmonary symptoms, eosinophilia, vasculitic rash, cardiac complications and/or neuropathy. This is a rare effect.
    1. TOXICITY: Four patients developed minimal adverse effects (eg, rash, upset stomach) after ingesting zafirlukast doses as high as 200 mg.
© 2011-2021 RightAnswer.com, Inc. and/or its licensors. All rights reserved. No claim to original U.S. Govt. works.