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|Example of Acute Exposure data from MEDITEXT.|
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Example Content from MEDITEXT for Antimony pentafluoride:
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ACUTE EXPOSURE INFORMATION
- Antimony pentafluoride is an oily, moderately viscous, colorless, water soluble, very reactive nonflammable liquid with a sharp or pungent odor used in the fluorination of organic compounds and as a catalyst. It reacts violently with water, releasing HYDROGEN FLUORIDE and other substances with release of heat.
- Inhalation and dermal exposure to antimony pentafluoride has caused cough, wheezing, dyspnea, chest tightness, pulmonary edema, and severe skin burns.
- Antimony poisoning resembles arsenic poisoning; in ingestions, antimony may cause more severe vomiting. In ingestions, violent vomiting, diarrhea, mucosal irritation, and sloughing of mucosal cells may be seen from the antimony component. Death is due to hypovolemia and shock from the corrosive effects and hypocalcemia, hypomagnesemia, and hyperkalemia and associated cardiac effects.
- Exposure to antimony salts may result in irritation of skin and mucous membranes.
- Antimony pentafluoride causes corrosive burns or irritation of the eyes, skin, and mucous membranes. If ingested, vomiting and severe burns of the oral cavity and throat may occur; bloody diarrhea may develop. Systemic absorption by any route can lead to bradycardia, hypotension, coma, seizures, and cardiac arrest.
- Myocardial injury with decreased contractility and electrical activity and higher excitability, jaundice, dyspnea, weight loss, alopecia, albuminuria, glomerular nephritis, splenic hyperplasia, elevated erythrocyte counts, and decreased leukocyte counts may be seen with chronic antimony exposure.
- Chronic inhalation exposure can lead to interstitial pneumonitis, lipoid deposits in the pulmonary alveoli, and cardiac and liver damage. Dermatitis, keratitis, conjunctivitis, and nasal septum perforation may occur with chronic exposure to antimony dusts.
- Antimony pentafluoride releases toxic and irritating fumes of fluoride and antimony when heated to decomposition. It reacts violently with water, releasing HYDROGEN FLUORIDE and other substances with release of heat.
- Users may REFER to the HYDROGEN FLUORIDE and ANTIMONY managements for MORE INFORMATION.
- HYDROGEN FLUORIDE TOXICITY -
- Hydrofluoric acid (HF) is corrosive to skin and mucous membranes. Exposure can result in pneumonitis, eye damage, GI erosion, and severe burns. The severity and rapidity of onset of signs and symptoms depends on the concentration of the acid, duration of exposure and penetrability of the exposed tissue. The pain from burns may be delayed so that the patient does not know he has been burned until some hours later.
- Dermal exposure to solutions containing greater than 50 percent HF produces immediate burning, erythema and tissue damage whereas exposure to 20 to 50 percent HF results in pain and erythema which may be delayed up to 1 to 8 hours. Exposure to solutions containing less than 20 percent HF results in erythema and pain delayed up to 24 hours after exposure.
- Systemic fluoride toxicity may result from ingestion, inhalation or extensive dermal burns and cause hypocalcemia, hypomagnesemia, hyperkalemia, pulmonary edema, metabolic acidosis, and death.
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