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|Example of Acute Exposure data from MEDITEXT.|
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Example Content from MEDITEXT for 67-63-0:
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ACUTE EXPOSURE INFORMATION
- USES: Primarily used as a topical antiseptic. Typical household preparations contain 70% isopropanol. Also used as a solvent in many household, cosmetic, and topical pharmaceutical products. Isopropanol baths are occasionally used in some cultural practices to relieve fevers.
- TOXICOLOGY: CNS depressant and gastrointestinal (GI) irritant; acetone (metabolite) likely contributes to CNS depression.
- EPIDEMIOLOGY: The most common toxic alcohol exposure reported to poison centers in the United States. Cases occur in the thousands, but toxicity is rarely severe.
- WITH POISONING/EXPOSURE
- MILD TO MODERATE TOXICITY: May include CNS depression, dysarthria, ataxia, nystagmus, similar to ethanol intoxication, nausea/vomiting, flushing, headache, tachycardia, mild hyperglycemia, ketonuria, and ketonemia WITHOUT metabolic acidosis.
- SEVERE TOXICITY: May include hemorrhagic gastritis, hypotension, respiratory depression, and coma. Death is rare and likely secondary to respiratory depression and aspiration.
- EYE EXPOSURE: Splash or vapor exposure causes irritation.
- DERMAL EXPOSURE: Repeated dermal application can cause systemic toxicity (primarily CNS depression), especially in infants and young children, because of more extensive dermal absorption and greater surface area-to-volume ratios.
- PARENTERAL EXPOSURE: CNS and respiratory depression are possible; hemolysis has developed in 1 patient.
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