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Example Content from MEDITEXT for 231277-92-2:
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ACUTE EXPOSURE INFORMATION
- WITH THERAPEUTIC USE
- The most common adverse reactions following administration of lapatinib in combination with capecitabine include diarrhea, nausea, vomiting, rash, and hand-foot syndrome.
- WITH POISONING/EXPOSURE
- Lapatinib overdose information is limited. The signs and symptoms of an acute overdose are expected to be similar to excessive pharmacologic effects. Grade 3 diarrhea and vomiting occurred in one patient who received 3000 mg of lapatinib for 10 days. Dose related QTc prolongation has been reported.
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