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Example Content from MEDITEXT for 107-15-3:
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ACUTE EXPOSURE INFORMATION
- Ethylenediamine (EDA) is an eye and mucous membrane irritant and skin sensitizer. EDA hypersensitivity is common, particularly in patients with contact dermatitis.
- EDA hypersensitivity reactions can occur following administration of aminophylline to patients previously sensitized by topical or inhalation routes. Skin reaction can be local, generalized, or exfoliative and may be accompanied by bronchospasm.
- Patients allergic to aminophylline may safely be given other theophylline preparations, but should avoid compounds closely related to EDA such as hydroxyzine.
- Poisoning may occur following inhalation, dermal, and oral exposure.
- When heated to decomposition, ethylenediamine emits toxic fumes of oxides of nitrogen and ammonia.
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