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|Example of Acute Exposure data from MEDITEXT.|
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Example Content from MEDITEXT for 100-42-5:
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ACUTE EXPOSURE INFORMATION
- Styrene may be irritating to the eyes, skin, and mucous membranes. It can be ototoxic, nephrotoxic and hepatotoxic, and is a CNS depressant. Signs and symptoms of exposure may include nausea, fatigue, headache, loss of coordination, muscle weakness, a feeling of drunkenness, dizziness, and unconsciousness.
- Peripheral neuropathy and pulmonary edema may occur. Prolonged or repeated exposure may lead to defatting dermatitis. Fetotoxicity has been observed in experimental animals and genotoxicity has been observed in vitro.
- The International Agency for Research on Cancer (IARC) has classified styrene as possibly carcinogenic to humans (Class 2B). Styrene-7,8-oxide, a metabolite of styrene, is classified in Group 2A (probably carcinogenic to humans) by the IARC.
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